Age-Dependent Metabolic and Immunosuppressive Effects of Tacrolimus
نویسندگان
چکیده
منابع مشابه
Gingival Overgrowth in Subjects under Immunosuppressive Regimens Based on Tacrolimus or Combination of Tacrolimus and Amlodipine
Tacrolimus has been used successfully to prevent acute rejection of renal transplantation. It inhibits calcineurin, a Ca2+ calmodulindependent phosphatase, which results in reduced expression of interleukin-2 by T lymphocytes [17]. Tacrolimus has been associated with many side effects including nephrotoxicity, neurotoxicity and the induction of a diabetic state. Unlike cyclosporine A, studies t...
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15 صفحه اولSignificance of Tacrolimus Monitoring to Optimize Immunosuppressive Therapy
Liver transplantation is the surgical treatment of choice for several irreversible liver diseases where a partially or completely diseased liver is replaced with a healthy liver. The continued use of immunosuppressant causes certain serious consequences such as hepatotoxicity, nephrotoxicity and post-transplant hyperglycemia. Inter individual variation has necessitated frequent monitoring of ta...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2016
ISSN: 1600-6135
DOI: 10.1111/ajt.14087